ChIP Antibodies

KCNA1 Rabbit Polyclonal Antibody (CAB16906)

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SKU:
CAB16906
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
Reactivity:
Human, Mouse, Rat
Synonyms:
EA1, MK1, AEMK, HBK1, HUK1, MBK1, RBK1, KV1.1, KCNA1
Research Use:
Signal Transduction
Frequently bought together:

Description

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KCNA1 Antibody (CAB16906)

The KCNA1 Antibody (CAB16906) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is specifically reactive with human samples and has been validated for use in Western blotting applications.The KCNA1 antibody binds to the KCNA1 protein, allowing for its detection and analysis in a variety of cell types. This makes it ideal for studies in neuroscience, neurology, and ion channel research.

This antibody is validated for use in WB, ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:KCNA1 Antibody
SKU:CAB16906
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:QLLH VSSP NLAS DSDL SRRS SSTM SKSE YMEI EEDM NNSI AHYR QVNI RTAN CTTA NQNC VNKS KLLT DV
Tested Applications:WB ELISA IF-P
Recommended Dilution:
WB1:500 - 1:1000
IF-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:EA1, MK1, AEMK, HBK1, HUK1, MBK1, RBK1, KV1.1, KCNA1
Positive Sample:HeLa, Mouse brain, Mouse spinal cord, Rat brain
Cellular Localization:Cell Junction, Cell Membrane, Cell Projection, Cytoplasmic Vesicle, Endoplasmic Reticulum, Membrane, Multi-Pass Membrane Protein, Perikaryon, Axon, Dendrite, Presynaptic Cell Membrane, Synapse.
Calculated MW:56kDa
Observed MW:60kDa/75kDa

This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

Purification MethodAffinity purification
Gene ID3736
RRIDAB_2770041
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates, using KCNA1 Rabbit pAb (CAB16906) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
Product ImageWestern blot analysis of lysates from HeLa cells, using KCNA1 Rabbit pAb (CAB16906) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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