Cell Biology Antibodies 10

INTS6 Rabbit Polyclonal Antibody (CAB6634)

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SKU:
CAB6634
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse
Synonyms:
HDB, INT6, DBI-1, DDX26, DICE1, DDX26A, Notchl2, INTS6
Research Use:
Cell Biology
Frequently bought together:

Description

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INTS6 Antibody (CAB6634)

The INTS6 Antibody (CAB6634) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the INTS6 protein, this antibody allows for the detection and analysis of INTS6 expression in a variety of cell types, making it an ideal reagent for research in the fields of molecular biology and oncology.INTS6 is a crucial player in the cellular response to DNA damage, functioning as part of the Integrator complex involved in RNA processing and DNA repair pathways.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:INTS6 Antibody
SKU:CAB6634
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MPIL LFLI DTSA SMNQ RSHL GTTY LDTA KGAV ETFM KLRA RDPA SRGD RYML VTFE EPPY AIKA GWKE NHAT FMNE LKNL QAEG LTTL GQSL RTAF DLLN LNRL VTGI DNYG QGRN PFFL EPAI IITI TDGS KLTT TSGV QDEL HLPL NSPL PGSE LTKE PFRW DQRL FALV LRLP GTMS VESE QLTG VPLD DSAI TPMC EVTG GRSY SVCS PRML NQCL ESLV QKVQ SGVV INFE KAGP DPSP VEDG QPDI SRPF GSQP WHSC HKLI YVRP NPKT GVPI
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:HDB, INT6, DBI-1, DDX26, DICE1, DDX26A, Notchl2, INTS6
Positive Sample:HepG2, Mouse testis
Cellular Localization:Nucleus.
Calculated MW:100kDa
Observed MW:117kDa

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and is located in the critical region of loss of heterozygosity (LOH). Multiple transcript variants encoding different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID26512
RRIDAB_2767223
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using INTS6 Rabbit pAb (CAB6634) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
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