Cell Biology Antibodies 10

IL22 Rabbit Polyclonal Antibody (CAB6216)

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SKU:
CAB6216
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
TIFa, IL-21, IL-22, ILTIF, IL-TIF, IL-D110, zcyto18, TIFIL-23, IL22
Research Use:
Cell Biology
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Description

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IL22 Antibody (CAB6216)

The IL22 Antibody (CAB6216) is a high-quality antibody developed for reliable detection and analysis of target proteins. Interleukin-22 is a cytokine that plays a crucial role in the regulation of tissue homeostasis and the defense against pathogens.This antibody, generated in rabbits, is highly specific for IL-22 and has been validated for use in Western blot applications. It binds specifically to IL-22, allowing for the detection and analysis of IL-22 in various cell types and tissue samples.IL-22 has been implicated in a variety of immune-related diseases, including inflammatory bowel disease, psoriasis, and cancer.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:IL22 Antibody
SKU:CAB6216
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:APIS SHCR LDKS NFQQ PYIT NRTF MLAK EASL ADNN TDVR LIGE KLFH GVSM SERC YLMK QVLN FTLE EVLF PQSD RFQP YMQE VVPF LARL SNRL STCH IEGD DLHI QRNV QKLK DTVK KLGE SGEI KAIG ELDL LFMS LRNA CI
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:TIFa, IL-21, IL-22, ILTIF, IL-TIF, IL-D110, zcyto18, TIFIL-23, IL22
Positive Sample:HL-60
Cellular Localization:Secreted.
Calculated MW:20kDa
Observed MW:16kDa

This gene is a member of the IL10 family of cytokines that mediate cellular inflammatory responses. The encoded protein functions in antimicrobial defense at mucosal surfaces and in tissue repair. This protein also has pro-inflammatory properties and plays a role in in the pathogenesis of several intestinal diseases. The encoded protein is a crucial cytokine that regulates host immunity in infectious diseases, including COVID-19 (disease caused by SARS-CoV-2).

Purification MethodAffinity purification
Gene ID50616
RRIDAB_2766826
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from HL-60 cells, using IL22 Rabbit pAb (CAB6216) at 1:900 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
Product ImageImmunofluorescence analysis of HL-60 cells using IL22 Rabbit pAb (CAB6216) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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