Immunology Antibodies 2

IL18R1 Rabbit Polyclonal Antibody (CAB2706)

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SKU:
CAB2706
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
CD218a, IL18RA, IL1RRP, CDw218a, IL-1Rrp, IL-18Ralpha, IL18Ralpha2, IL-18R-alpha, IL18R1/IL-18 R alpha
Research Use:
Immunology
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Description

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IL18R1 Antibody (CAB2706)

The IL18R1 Antibody (CAB2706) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced by Assay Genie, is specifically designed for use with human samples and has been validated for Western blot applications.IL18R1, also known as interleukin-18 receptor 1, plays a crucial role in mediating the effects of interleukin-18, a pro-inflammatory cytokine. By targeting IL18R1 with this polyclonal antibody, researchers can detect and analyze the expression of the receptor in various cell types, providing insights into its function in immunology and inflammatory conditions.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:IL18R1 Antibody
SKU:CAB2706
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:AESC TSRP HITV VEGE PFYL KHCS CSLA HEIE TTTK SWYK SSGS QEHV ELNP RSSS RIAL HDCV LEFW PVEL NDTG SYFF QMKN YTQK WKLN VIRR NKHS CFTE RQVT SKIV EVKK FFQI TCEN SYYQ TLVN STSL YKNC KKLL LENN KNPT IKKN AEFE DQGY YSCV HFLH HNGK LFNI TKTF NITI VEDR SNIV PVLL GPKL NHVA VELG KNVR LNCS ALLN EEDV IYWM FGEE NGSD PNIH EEKE MRIM TPEG KWHA SKVL RIEN IGES NLNV LYNC TVAS TGGT DTKS FILV RKAD MA
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:200
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CD218a, IL18RA, IL1RRP, CDw218a, IL-1Rrp, IL-18Ralpha, IL18Ralpha2, IL-18R-alpha, IL18R1/IL-18 R alpha
Positive Sample:NCI-H460
Cellular Localization:Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:62kDa
Observed MW:75kDa

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID8809
RRIDAB_2764561
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from NCI-H460 cells, using IL18R1/IL-18 R alpha Rabbit pAb (CAB2706) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human colon carcinoma using IL18R1/IL-18 R alpha Rabbit pAb (CAB2706) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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