Cell Biology Antibodies 11

GYPB Rabbit Polyclonal Antibody (CAB7682)

(No reviews yet) Write a Review
SKU:
CAB7682
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse
Synonyms:
SS, GPB, GYP, MNS, GYPA, PAS-3, CD235b, GYPB
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

GYPB Antibody (CAB7682)

The GYPB Antibody (CAB7682) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to the GYPB protein, this antibody enables researchers to detect and analyze GYPB expression in a variety of cell types.The GYPB protein is important for determining blood group antigens, specifically the MNS blood group system.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:GYPB Antibody
SKU:CAB7682
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:MYGK IIFV LLLS EIVS ISAL STTE VAMH TSTS SSVT KSYI SSQT NGET GQLV HRFT VPAP VVII LIIL CVMA GIIG TILL ISYT IRRL IKA
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:SS, GPB, GYP, MNS, GYPA, PAS-3, CD235b, GYPB
Positive Sample:Human serum
Cellular Localization:Cell Membrane, Single-Pass Type I Membrane Protein.
Calculated MW:10kDa
Observed MW:25kDa

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID2994
RRIDAB_2769723
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Human serum, using GYPB Rabbit pAb (CAB7682) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
View AllClose

0 Reviews

View AllClose

Related Products