Cell Biology Antibodies 8

IL13 Rabbit Polyclonal Antibody (CAB2089)

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SKU:
CAB2089
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse
Synonyms:
P600, IL-13, IL13
Research Use:
Cell Biology
Frequently bought together:

Description

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IL13 Antibody (CAB2089)

The IL13 Antibody (CAB2089) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, has high reactivity with samples from various species, including human, and has been validated for use in applications such as Western blotting.Interleukin-13 is known for its role in promoting allergic responses and has been implicated in diseases such as asthma and inflammatory conditions. By using the Interleukin-13 Polyclonal Antibody, researchers can detect and analyze interleukin-13 levels in different cell types, providing insights into its function in these disease processes.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:IL13 Antibody
SKU:CAB2089
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:LTCL GGFA SPGP VPPS TALR ELIE ELVN ITQN QKAP LCNG SMVW SINL TAGM YCAA LESL INVS GCSA IEKT QRML SGFC PHKV SAGQ FSSL HVRD TKIE VAQF VKDL LLHL KKLF REGQ FN
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:100
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:P600, IL-13, IL13
Positive Sample:U-937, K-562
Cellular Localization:Secreted.
Calculated MW:16kDa
Observed MW:16kDa

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Purification MethodAffinity purification
Gene ID3596
RRIDAB_2764109
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from U-937 cells, using IL13 Rabbit pAb (CAB2089) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 45s.
Product ImageWestern blot analysis of lysates from K-562 cells, using IL13 Rabbit pAb (CAB2089) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human stomach using IL13 Rabbit pAb (CAB2089) (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
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