Epigenetics & Nuclear Signaling Antibodies 2

HNRNPH1 Rabbit Polyclonal Antibody (CAB5924)

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SKU:
CAB5924
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse, Rat
Synonyms:
HNRPH, HNRPH1, NEDCDS, hnRNPH, HNRNPH1
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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HNRNPH1 Antibody (CAB5924)

The HNRNPH1 Antibody (CAB5924) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, has high specificity for human samples and has been validated for use in Western blot applications.HNRNPH1 plays a crucial role in the regulation of gene expression and alternative splicing, making it a key player in various biological processes. Its dysregulation has been linked to diseases such as cancer, neurodevelopmental disorders, and autoimmune conditions, highlighting the importance of studying its function and mechanism of action.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:HNRNPH1 Antibody
SKU:CAB5924
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:VRTH YDPP RKLM AMQR PGPY DRPG AGRG YNSI GRGA GFER MRRG AYGG GYGG YDDY NGYN DGYG FGSD RFGR DLNY CFSG MSDH RYGD GGST FQST TGHC VHMR GLPY RATE NDIY NFFS PLNP VRVH IEIG PDGR VTGE ADVE FATH EDAV AAMS KDKA NMQH RYVE LFLN STAG ASGG AYEH RYVE LFLN STAG ASGG AYGS QMMG GMGL SNQS SYGG PASQ QLSG GYGG GYGG QSSM SGYD QVLQ ENSS DFQS NIA
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:1000 - 1:5000
IHC-P1:50 - 1:200
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:HNRPH, HNRPH1, NEDCDS, hnRNPH, HNRNPH1
Positive Sample:Rat testis, Rat brain
Cellular Localization:Nucleus, Nucleoplasm.
Calculated MW:49kDa
Observed MW:55kDa

This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described

Purification MethodAffinity purification
Gene ID3187
RRIDAB_2766663
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using HNRNPH1 Rabbit pAb (CAB5924) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageWestern blot analysis of various lysates using HNRNPH1 Rabbit pAb (CAB5924) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Mouse kidney using HNRNPH1 Rabbit pAb (CAB5924) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat ovary using HNRNPH1 Rabbit pAb (CAB5924) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
Product ImageImmunofluorescence analysis of 293T cells using HNRNPH1 Rabbit pAb (CAB5924) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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