Cell Biology Antibodies 12

GHRHR Rabbit Polyclonal Antibody (CAB8421)

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SKU:
CAB8421
Product Type:
Antibody
Applications:
WB
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
GRFR, GHRFR, IGHD4, IGHD1B, GHRHR
Research Use:
Cell Biology
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Description

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GHRHR Antibody (CAB8421)

The GHRHR Antibody (CAB8421) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for Western blot applications.GHRHR is a crucial component of the growth hormone axis, playing a pivotal role in growth, metabolism, and other biological functions. Dysregulation of GHRHR signaling has been linked to growth disorders, metabolic disorders, and other health conditions, making it an attractive target for therapeutic intervention.

This antibody is validated for use in WB, ELISA, IF-P applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:GHRHR Antibody
SKU:CAB8421
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MDRR MWGA HVFC VLSP LPTV LGHM HPEC DFIT QLRE DESA CLQA AEEM PNTT LGCP ATWD GLLC WPTA GSGE WVTL PCPD FFSH FSSE SGAV KRDC TITG WSEP FPPY PVAC PVPL ELLA EEES YFST VK
Tested Applications:WB ELISA IF-P
Recommended Dilution:
WB1:100 - 1:500
IF-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:GRFR, GHRFR, IGHD4, IGHD1B, GHRHR
Positive Sample:Mouse brain, Rat brain
Cellular Localization:Cell Membrane, Multi-Pass Membrane Protein.
Calculated MW:47kDa
Observed MW:45kDa

This gene encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature.

Purification MethodAffinity purification
Gene ID2692
RRIDAB_2769601
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates, using GHRHR Rabbit pAb (CAB8421) at 1:400 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
Product ImageImmunofluorescence analysis of paraffin-embedded rat pituitary gland using GHRHR Rabbit pAb (CAB8421) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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