Cell Biology Antibodies 10

GDAP1 Rabbit Polyclonal Antibody (CAB6601)

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SKU:
CAB6601
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
CMT4, CMT4A, CMTRIA, GDAP1
Research Use:
Cell Biology
Frequently bought together:

Description

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GDAP1 Antibody (CAB6601)

The GDAP1 Antibody (CAB6601) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, shows high reactivity with human samples and is validated for use in Western blot applications.GDAP1, or ganglioside-induced differentiation-associated protein 1, is important for maintaining mitochondrial function and proper nerve cell development. Mutations in the GDAP1 gene can lead to neurological disorders like CMT, a group of inherited neuropathies.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:GDAP1 Antibody
SKU:CAB6601
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MRLN STGE VPVL IHGE NIIC EATQ IIDY LEQT FLDE RTPR LMPD KESM YYPR VQHY RELL DSLP MDAY THGC ILHP ELTV DSMI PAYA TTRI RSQI GNTE SELK KLAE ENPD LQEA YIAK QKRL KSKL LDHD NVKY LKKI LDEL EKVL DQVE TELQ RRNE ETPE EGQQ PWLC GESF TLAD VSLA VTLH RLKF LGFA RRNW GNGK RPNL ETYY ERVL KRKT FNKV L
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CMT4, CMT4A, CMTRIA, GDAP1
Positive Sample:MCF7, HepG2, Mouse brain, Mouse spinal cord, Rat brain
Cellular Localization:Cytoplasm, Mitochondrion Outer Membrane, Multi-Pass Membrane Protein.
Calculated MW:41kDa
Observed MW:38kDa

This gene encodes a member of the ganglioside-induced differentiation-associated protein family, which may play a role in a signal transduction pathway during neuronal development. Mutations in this gene have been associated with various forms of Charcot-Marie-Tooth Disease and neuropathy. Two transcript variants encoding different isoforms and a noncoding variant have been identified for this gene.

Purification MethodAffinity purification
Gene ID54332
RRIDAB_2767192
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using GDAP1 Rabbit pAb (CAB6601) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat kidney using GDAP1 Rabbit pAb (CAB6601) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Mouse kidney using GDAP1 Rabbit pAb (CAB6601) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
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