Cell Biology Antibodies 13

EXOSC10 Rabbit Polyclonal Antibody (CAB17519)

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SKU:
CAB17519
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
p2, p3, p4, RRP6, PMSCL, Rrp6p, PM-Scl, PMSCL2, PM/Scl-100, EXOSC10
Research Use:
Cell Biology
Frequently bought together:

Description

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EXOSC10 Antibody (CAB17519)

The EXOSC10 Antibody (CAB17519) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for Western blot applications. By binding to the ExoSC10 protein, researchers can effectively detect and analyze this critical molecule in a variety of cell types.ExoSC10 is essential for the proper formation and release of exosomes, extracellular vesicles that play important roles in intercellular communication and signaling. Dysregulation of exosome production has been implicated in various diseases, including cancer, neurodegenerative disorders, and infectious diseases.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:EXOSC10 Antibody
SKU:CAB17519
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:VAAG VKKS GPLP SAER LENV LFGP HDCS HAPP DGYP IIPT SGSV PVQK QASL FPDE KEDN LLGT TCLI ATAV ITLF NEPS AEDS KKGP LTVA QKKA QNIM ESFE NPFR MFLP SLGH RAPV SQAA KFDP STKI YEIS NRWK LAQV QVQK DSKE AVKK KAAE QTAA REQA KEAC KAAA EQAI SVRQ QVVL ENAA KKRE RATS DPRT TEQK QEKK RLKI SKKP KDPE PPEK EFTP YDYS QSDF KAFA GNSK SKVS SQFD PNKQ TPSG KKCI AAKK IKQS VGNK SMSF PTGK SDRG FRYN WPQR
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:p2, p3, p4, RRP6, PMSCL, Rrp6p, PM-Scl, PMSCL2, PM/Scl-100, EXOSC10
Positive Sample:A-549, Raji, Mouse testis, Mouse spleen, Mouse lung, Rat brain
Cellular Localization:Cytoplasm, Cytoplasmic Exosome (Rnase Complex), Cytosol, Nuclear Exosome (Rnase Complex), Nucleolar Exosome (Rnase Complex), Nucleolus, Nucleoplasm, Nucleus.
Calculated MW:101kDa
Observed MW:110kDa

Enables 3'-5'-exoribonuclease activity. Involved in several processes, including RNA catabolic process; maturation of 5.8S rRNA; and negative regulation of telomere maintenance via telomerase. Located in cytosol; nuclear lumen; and transcriptionally active chromatin. Part of nuclear exosome (RNase complex).

Purification MethodAffinity purification
Gene ID5394
RRIDAB_2769379
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using EXOSC10 Rabbit pAb (CAB17519) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
Product ImageWestern blot analysis of lysates from Rat brain, using EXOSC10 Rabbit pAb (CAB17519) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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