Cell Biology Antibodies 18

ERCC6 Rabbit Polyclonal Antibody (CAB18211)

(No reviews yet) Write a Review
SKU:
CAB18211
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
CSB, CKN2, COFS, ARMD5, COFS1, POF11, RAD26, UVSS1, CSB-PGBD3, ERCC6
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

ERCC6 Antibody (CAB18211)

The ERCC6 Antibody (CAB18211) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for Western blot applications. By binding to the ERCC6 protein, this antibody enables the detection and analysis of ERCC6 expression in various cell types, making it ideal for research in molecular biology and genomics.ERCC6, also known as Cockayne syndrome protein B (CSB), plays a crucial role in maintaining genomic stability by repairing DNA damage and promoting accurate transcription.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:ERCC6 Antibody
SKU:CAB18211
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:LPVF MEQF SVPI TMGG YSNA SPVQ VKTA YKCA CVLR DTIN PYLL RRMK SDVK MSLS LPDK NEQV LFCR LTDE QHKV YQNF VDSK EVYR ILNG EMQI FSGL I
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CSB, CKN2, COFS, ARMD5, COFS1, POF11, RAD26, UVSS1, CSB-PGBD3, ERCC6
Positive Sample:293T, A-549, Mouse thymus, Rat testis
Cellular Localization:B-Wich Complex, Nucleolus, Nucleoplasm, Nucleus, Transcription Elongation Factor Complex.
Calculated MW:168kDa
Observed MW:168kDa

This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3 (GeneID:267004), which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene.

Purification MethodAffinity purification
Gene ID2074
RRIDAB_2861987
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using ERCC6 Rabbit pAb (CAB18211) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageWestern blot analysis of various lysates using ERCC6 Rabbit pAb (CAB18211) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human tonsil using ERCC6 Rabbit pAb (CAB18211) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
View AllClose

0 Reviews

View AllClose

Related Products