Cell Death Antibodies 2

ELMO3 Rabbit Polyclonal Antibody (CAB7182)

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SKU:
CAB7182
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
Reactivity:
Human, Mouse, Rat
Synonyms:
CED12, CED-12, ELMO-3, ELMO3
Research Use:
Cell Death
Frequently bought together:

Description

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ELMO3 Antibody (CAB7182)

The ELMO3 Antibody (CAB7182) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody is produced in rabbits and has been extensively validated for its specificity and sensitivity in various experimental applications, with a particular focus on immunofluorescence and immunohistochemistry.ELMO3, a key regulator of Rac activation and actin cytoskeleton dynamics, plays a crucial role in cellular processes such as cell motility, adhesion, and phagocytosis.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:ELMO3 Antibody
SKU:CAB7182
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:NKTW KEMR ATQE DFDK VMQV VREQ LART LALK PTSL ELFR TKVN ALTY GEVL RLRQ TERL HQEG TLAP PILE LREK LKPE LMGL IRQQ RLLR LCEG TLFR KISS RRRQ DKLW FCCL SPNH KLLQ YGDM EEGA SPPT LESL PEQL PVAD MRAL LTGK DCPH VREK GSGK QNKD LYEL AFSI SYDR GEEE AYLN FIAP SKRE FYLW TDGL SALL GSPM GSEQ TRLD LEQL LTME TKLR LLEL ENVP IPER PPPV PPPP TNFN FCYD CSIA EP
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CED12, CED-12, ELMO-3, ELMO3
Positive Sample:22Rv1, SW480, HT-29, Mouse brain, Mouse liver, Mouse kidney, Rat lung
Cellular Localization:Cytoplasm.
Calculated MW:81kDa
Observed MW:81kDa

The protein encoded by this gene is similar to a C. elegans protein that functions in phagocytosis of apoptotic cells and in cell migration. Other members of this small family of engulfment and cell motility (ELMO) proteins have been shown to interact with the dedicator of cyto-kinesis 1 protein to promote phagocytosis and effect cell shape changes.

Purification MethodAffinity purification
Gene ID79767
RRIDAB_2767732
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using ELMO3 Rabbit pAb (CAB7182) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 30s.
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