Cell Biology Antibodies 17

DNM1 Rabbit Polyclonal Antibody (CAB18583)

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SKU:
CAB18583
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse, Rat
Synonyms:
DNM, DEE31, EIEE31, DNM1
Research Use:
Cell Biology
Frequently bought together:

Description

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DNM1 Antibody (CAB18583)

The DNM1 Antibody (CAB18583) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. It binds to the DNM1 protein, allowing for detection and analysis in various cell types, making it a crucial reagent for studies in cell biology, neurology, and cancer research.DNM1, also known as dynamin 1, plays a critical role in various cellular processes, including endocytosis, mitochondrial dynamics, and synaptic transmission.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:DNM1 Antibody
SKU:CAB18583
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:TGLF TPDM AFET IVKK QVKK IREP CLKC VDMV ISEL ISTV RQCT KKLQ QYPR LREE MERI VTTH IRER EGRT KEQV MLLI DIEL AYMN TNH
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:DNM, DEE31, EIEE31, DNM1
Positive Sample:SH-SY5Y, HeLa, 293T, C6
Cellular Localization:Cytoplasm, Cytoskeleton.
Calculated MW:97kDa
Observed MW:100kDa

This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.

Purification MethodAffinity purification
Gene ID1759
RRIDAB_2862343
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using DNM1 Rabbit pAb (CAB18583) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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