Cell Cycle Antibodies 1

Casein Kinase 1 alpha (CSNK1A1) Rabbit Polyclonal Antibody (CAB16225)

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SKU:
CAB16225
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Cycle
Reactivity:
Human, Mouse, Rat
Synonyms:
CK1, CK1a, CKIa, HLCDGP1, PRO2975, HEL-S-77p, Casein Kinase 1 alpha (CSNK1A1)
Research Use:
Cell Cycle
Frequently bought together:

Description

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Casein Kinase 1 alpha (CSNK1A1) Antibody (CAB16225)

The Casein Kinase 1 alpha (CSNK1A1) Antibody (CAB16225) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting CSNK1A1 in human samples, making it suitable for Western blot applications.CSNK1A1, also known as casein kinase 1 alpha 1, is a serine/threonine kinase that regulates the phosphorylation of numerous proteins involved in cell signaling pathways. Dysregulation of CSNK1A1 has been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic conditions.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:Casein Kinase 1 alpha (CSNK1A1) Antibody
SKU:CAB16225
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:EKKM STPV EVLC KGFP AEFA MYLN YCRG LRFE EAPD YMYL RQLF RILF RTLN HQYD YTFD WTML KQKA AQQA ASSS GQGQ QAQT PTGK QTDK TKSN MKGF
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CK1, CK1a, CKIa, HLCDGP1, PRO2975, HEL-S-77p, Casein Kinase 1 alpha (CSNK1A1)
Positive Sample:U-87MG, HeLa, MCF7, PC-3, Mouse brain
Cellular Localization:Chromosome, Cytoplasm, Nucleus Speckle, Centromere, Centrosome, Cytoskeleton, Kinetochore, Microtubule Organizing Center.
Calculated MW:39kDa
Observed MW:38kDa

Enables protein serine/threonine kinase activity. Involved in several processes, including negative regulation of canonical Wnt signaling pathway; peptidyl-serine phosphorylation; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in centrosome; cytosol; and nuclear speck. Part of beta-catenin destruction complex. Colocalizes with keratin filament and mRNA cleavage and polyadenylation specificity factor complex. Biomarker of Alzheimer's disease and inclusion body myositis.

Purification MethodAffinity purification
Gene ID1452
RRIDAB_2763680
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Casein Kinase 1 alpha (CSNK1A1) Rabbit pAb (CAB16225) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human tonsil using Casein Kinase 1 alpha (CSNK1A1) Rabbit pAb (CAB16225) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
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