Anti-Casein Kinase 1 alpha (CSNK1A1) Antibody (CAB9308)
- SKU:
- CAB9308
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
- Reactivity:
- Human, Mouse, Rat
- Synonyms:
- CK1, CK1a, CKIa, HLCDGP1, PRO2975, HEL-S-77p, Casein Kinase 1 alpha (CSNK1A1)
- Research Use:
- Cell Cycle
Description
Casein Kinase 1 alpha (CSNK1A1) Monoclonal Antibody (CAB9308)
The Casein Kinase 1 alpha (CSNK1A1) Monoclonal Antibody (CAB9308) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically targeting the CSNK1A1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for studies in molecular biology, cell signaling, and cancer research.CSNK1A1, also known as casein kinase 1 alpha, plays a crucial role in diverse cellular processes such as cell proliferation, differentiation, and metabolism.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
| Product Name: | Casein Kinase 1 alpha (CSNK1A1) Monoclonal Antibody |
| SKU: | CAB9308 |
| Size: | 20μL, 100μL |
| Reactivity: | Human, Mouse, Rat |
| Clone Number: | ARC1860 |
| Conjugate: | Unconjugated |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. | ||||||
| Sequence: | Email for sequence | ||||||
| Tested Applications: | WB IHC-P ELISA | ||||||
| Recommended Dilution: |
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| Synonyms: | CK1, CK1a, CKIa, HLCDGP1, PRO2975, HEL-S-77p, Casein Kinase 1 alpha (CSNK1A1) |
| Positive Sample: | HeLa, NIH/3T3, Jurkat, Mouse lung, Rat lung, Rat brain |
| Cellular Localization: | Chromosome, Cytoplasm, Nucleus Speckle, Centromere, Centrosome, Cytoskeleton, Kinetochore, Microtubule Organizing Center, Cilium Basal Body. |
| Calculated MW: | 39kDa |
| Observed MW: | 35kDa |
Enables protein serine/threonine kinase activity. Involved in several processes, including negative regulation of canonical Wnt signaling pathway; peptidyl-serine phosphorylation; and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in centrosome; cytosol; and nuclear speck. Part of beta-catenin destruction complex. Colocalizes with keratin filament and mRNA cleavage and polyadenylation specificity factor complex. Biomarker of Alzheimer's disease and inclusion body myositis.
| Purification Method | Affinity purification |
| Gene ID | 1452 |
| RRID | AB_2863708 |
| Buffer Information | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3. |
 | Western blot analysis of various lysates using Casein Kinase 1 alpha (CSNK1A1) Rabbit mAb (CAB9308) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s. |
 | Immunohistochemistry analysis of paraffin-embedded Rat liver using Casein Kinase 1 alpha (CSNK1A1) Rabbit mAb (CAB9308) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M Tris/EDTA Buffer (pH 9.0) prior to IHC staining. |
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