Anti-Contactin 2 Antibody (CAB5137)
- SKU:
- CAB5137
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- AXT
- Synonyms:
- FAME5
- Synonyms:
- TAG-1
- Synonyms:
- TAX
- Synonyms:
- TAX1
- Research Area:
- Cell Biology
Description
| Product Name: | Contactin 2 Rabbit mAb |
| Product Code: | CAB5137 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | AXT, FAME5, TAG-1, TAX, TAX1 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human Contactin 2 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | A-549, C6, SH-SY5Y, U-251MG, Mouse lung, Mouse spinal cord, Mouse brain, Rat brain |
| Immunogen: | A synthesized peptide derived from human Contactin 2 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 6900 |
| Uniprot: | Q02246 |
| Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor |
| Calculated MW: | 135kDa |
| Observed MW: | 150kDa |
| UniProt Protein Function: | CNTN2: May play a role in the initial growth and guidance of axons. May be involved in cell adhesion. Belongs to the immunoglobulin superfamily. Contactin family. |
| UniProt Protein Details: | Protein type:Membrane protein, GPI anchor; Cell adhesion Chromosomal Location of Human Ortholog: 1q32.1 Cellular Component: voltage-gated potassium channel complex; cell surface; cell soma; integral to plasma membrane; plasma membrane; synapse; myelin sheath Molecular Function:identical protein binding; protein self-association; carbohydrate binding; glycoprotein binding Biological Process: axon guidance; cerebral cortex GABAergic interneuron migration; myelination in the central nervous system; positive regulation of adenosine receptor signaling pathway; axonal fasciculation; regulation of astrocyte differentiation; microtubule cytoskeleton organization and biogenesis; learning; adult walking behavior; negative regulation of neuron differentiation; receptor internalization; clustering of voltage-gated potassium channels; regulation of axon diameter; cell adhesion; regulation of neuronal synaptic plasticity Disease: Epilepsy, Familial Adult Myoclonic, 5 |
| NCBI Summary: | The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. It may also be involved in glial tumorigenesis and may provide a potential target for therapeutic intervention. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q02246 |
| NCBI GenInfo Identifier: | 4827022 |
| NCBI Gene ID: | 6900 |
| NCBI Accession: | NP_005067.1 |
| UniProt Secondary Accession: | Q02246,P78432, Q5T054, |
| UniProt Related Accession: | Q02246 |
| Molecular Weight: | |
| NCBI Full Name: | contactin-2 |
| NCBI Synonym Full Names: | contactin 2 (axonal) |
| NCBI Official Symbol: | CNTN2 |
| NCBI Official Synonym Symbols: | AXT; TAX; TAX1; FAME5; TAG-1 |
| NCBI Protein Information: | contactin-2; axonal glycoprotein TAG-1; axonin-1 cell adhesion molecule; transient axonal glycoprotein 1; contactin 2 (transiently expressed); transiently-expressed axonal glycoprotein |
| UniProt Protein Name: | Contactin-2 |
| UniProt Synonym Protein Names: | Axonal glycoprotein TAG-1; Axonin-1; Transient axonal glycoprotein 1; TAX-1 |
| Protein Family: | Contactin |
| UniProt Gene Name: | CNTN2 |
| UniProt Entry Name: | CNTN2_HUMAN |
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