Cell Biology Antibodies 14

CHRM1 Rabbit Polyclonal Antibody (CAB16819)

(No reviews yet) Write a Review
SKU:
CAB16819
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
M1, HM1, M1R, CHRM1
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

CHRM1 Antibody (CAB16819)

The CHRM1 Antibody (CAB16819) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbit serum, is highly specific for human samples and is validated for use in Western blot applications. By binding to the CHRM1 protein, the antibody enables accurate detection and analysis in a variety of cell types, making it ideal for studies in neurology, pharmacology, and drug development.CHRM1 is an important receptor in the central and peripheral nervous systems, where it plays a crucial role in mediating the effects of acetylcholine.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:CHRM1 Antibody
SKU:CAB16819
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:MNTS APPA VSPN ITVL APGK GPWQ VAFI GITT GLLS LATV TGNL LVLI SFKV NTEL KTVN NYFL LSLA CADL IIGT FSMN LYTT YLLM GHWA LGTL ACDL
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:1000 - 1:5000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:M1, HM1, M1R, CHRM1
Positive Sample:Mouse brain, Rat brain
Cellular Localization:Cell Junction, Cell Membrane, Multi-Pass Membrane Protein, Postsynaptic Cell Membrane, Synapse.
Calculated MW:51kDa
Observed MW:51kDa

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.

Purification MethodAffinity purification
Gene ID1128
RRIDAB_2768907
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using CHAbGn1 Rabbit pAb (CAB16819) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunofluorescence analysis of OVCAR-3 cells using CHAbGn1 Rabbit pAb (CAB16819) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product ImageImmunofluorescence analysis of NIH-3T3 cells using CHAbGn1 Rabbit pAb (CAB16819) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product ImageImmunofluorescence analysis of OVCAR-3 cells using CHAbGn1 Rabbit pAb (CAB16819) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
View AllClose

0 Reviews

View AllClose

Related Products