Cell Biology Antibodies 6

CHRM1 Rabbit Polyclonal Antibody (CAB1598)

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SKU:
CAB1598
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
M1, HM1, M1R, CHRM1
Research Use:
Cell Biology
Frequently bought together:

Description

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CHRM1 Antibody (CAB1598)

The CHRM1 Antibody (CAB1598) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the CHRM1 protein, this antibody allows for accurate detection and analysis in a range of cell types, making it an excellent choice for studies in neuroscience, pharmacology, and drug discovery.The CHRM1 receptor is a G protein-coupled receptor that plays a crucial role in mediating the effects of acetylcholine in the central and peripheral nervous systems.

This antibody is validated for use in WB, IHC-P, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:CHRM1 Antibody
SKU:CAB1598
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:SPET PPGR CCRC CRAP RLLQ AYSW KEEE EEDE GSME SLTS SEGE EPGS EVVI KMPM VDPE AQAP TKQP PRSS PNTV KRPT KKGR DRAG KGQK PRGK EQLA
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IHC-P1:50 - 1:200
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:M1, HM1, M1R, CHRM1
Positive Sample:SH-SY5Y, U-87MG, C6
Cellular Localization:Cell Junction, Cell Membrane, Multi-Pass Membrane Protein, Postsynaptic Cell Membrane, Synapse.
Calculated MW:51kDa
Observed MW:51kDa

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.

Purification MethodAffinity purification
Gene ID1128
RRIDAB_2763418
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using CHAbGn1 Rabbit pAb (CAB1598) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Mouse brain using CHAbGn1 Rabbit pAb (CAB1598) at dilution of 1:200 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
Product ImageImmunofluorescence analysis of SH-SY5Y cells using CHAbGn1 Rabbit pAb (CAB1598) at dilution of 1:200 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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