Cell Cycle Antibodies 1

CDK7 Rabbit Polyclonal Antibody (CAB12942)

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SKU:
CAB12942
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Cycle
Reactivity:
Human, Mouse, Rat
Synonyms:
CAK, CAK1, HCAK, MO15, STK1, CDKN7, p39MO15, K7
Research Use:
Cell Cycle
Frequently bought together:

Description

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CDK7 Antibody (CAB12942)

The CDK7 Antibody (CAB12942) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, demonstrates high specificity and sensitivity in detecting CDK7 in human samples, making it ideal for use in Western blot experiments. By targeting CDK7, researchers can gain insights into its role in controlling cell growth and gene expression, crucial for understanding cancer development and identifying potential therapeutic targets.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:CDK7 Antibody
SKU:CAB12942
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:PFLP GDSD LDQL TRIF ETLG TPTE EQWP DMCS LPDY VTFK SFPG IPLH HIFS AAGD DLLD LIQG LFLF NPCA RITA TQAL KMKY FSNR PGPT PGCQ LPRP NCPV ETLK EQSN PALA IKRK RTEA LEQG GLPK KLIF
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:1000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CAK, CAK1, HCAK, MO15, STK1, CDKN7, p39MO15, K7
Positive Sample:293T
Cellular Localization:Cytoplasm, Nucleus, Perinuclear Region.
Calculated MW:39kDa
Observed MW:40kDa

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.

Purification MethodAffinity purification
Gene ID1022
RRIDAB_2759789
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using [KO Validated] CDK7 Rabbit pAb (CAB12942) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 15s.
Product ImageWestern blot analysis of lysates from wild type (WT) and CDK7 knockout (KO) 293T cells, using [KO Validated] CDK7 Rabbit pAb (CAB12942) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 180s.
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