Cell Biology Antibodies 8

CDC37 Rabbit Polyclonal Antibody (CAB2859)

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SKU:
CAB2859
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse
Synonyms:
P50CDC37, CDC37
Research Use:
Cell Biology
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Description

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CDC37 Antibody (CAB2859)

The CDC37 Antibody (CAB2859) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By targeting the CDC37 protein, this antibody allows for precise detection and analysis in various cell types, making it an ideal tool for studies in cell biology and cancer research.CDC37 is a crucial regulator of protein kinase activity, playing a key role in the folding and maturation of these important signaling molecules.

This antibody is validated for use in WB, IP, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:CDC37 Antibody
SKU:CAB2859
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MVDY SVWD HIEV SDDE DETH PNID TASL FRWR HQAR VERM EQFQ KEKE ELDR GCRE CKRK VAEC QRKL KELE VAEG GKAE LERL QAEA QQLR KEER SWEQ KLEE MRKK EKSM PWNV DTLS KDGF SKSM VNTK PEKT EEDS EEVR EQKH KTFV EKYE KQIK
Tested Applications:WB IP ELISA
Recommended Dilution:
WB1:200 - 1:1000
IP0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:P50CDC37, CDC37
Positive Sample:Raji, HeLa, HepG2, BT474, HT-1080
Cellular Localization:Cytoplasm.
Calculated MW:44kDa
Observed MW:50kDa

The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

Purification MethodAffinity purification
Gene ID11140
RRIDAB_2764684
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using CDC37 Rabbit pAb (CAB2859) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
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