Epigenetics & Nuclear Signaling Antibodies 2

CBX8 Rabbit Polyclonal Antibody (CAB6222)

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SKU:
CAB6222
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse, Rat
Synonyms:
PC3, RC1, CBX8
Research Use:
Epigenetics and Nuclear Signaling
Frequently bought together:

Description

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CBX8 Antibody (CAB6222)

The CBX8 Antibody (CAB6222) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blotting applications.CBX8 is a crucial component of the polycomb repressive complex 1 (PRC1), which plays a key role in gene silencing and chromatin compaction. By targeting CBX8, researchers can investigate its function in various cellular processes, such as gene expression regulation, cell differentiation, and development.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:CBX8 Antibody
SKU:CAB6222
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:LLKA QAKA KAKT YEFR SDSA RGIR IPYP GRSP QDLA STSR AREG LRNM GLSP PASS TSTS STCR AEAP RDRD RDRD RDRE RDRE RERE RERE RERE RERE RGTS RVDD KPSS PGDS SKKR GPKP RKEL PDPS QRPL GEPS AGLG EYLK GRKL DDTP SGAG KFPA GHSV IQLA RRQD SDLV QCGV TSPS SAEA TGKL AVDT F
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PC3, RC1, CBX8
Positive Sample:A-549, 293T, HeLa, MCF-7, Mouse thymus
Cellular Localization:Nucleus.
Calculated MW:43kDa
Observed MW:50kDa

Enables methylated histone binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in chromatin and nucleoplasm. Part of PRC1 complex. Biomarker of esophagus squamous cell carcinoma and glioblastoma.

Purification MethodAffinity purification
Gene ID57332
RRIDAB_2766831
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using CBX8 Rabbit pAb (CAB6222) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat pancreas using CBX8 Rabbit pAb (CAB6222) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
Product ImageImmunohistochemistry analysis of paraffin-embedded Mouse testis using CBX8 Rabbit pAb (CAB6222) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
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