Signal Transduction Antibodies 3

CBLC Rabbit Polyclonal Antibody (CAB7789)

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SKU:
CAB7789
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
Reactivity:
Human, Mouse
Synonyms:
CBL-3, RNF57, CBL-SL, CBLC
Research Use:
Signal Transduction
Frequently bought together:

Description

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CBLC Antibody (CAB7789)

The CBLC Antibody (CAB7789) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the Cblc protein, this antibody enables precise detection and analysis in various cell types, making it an invaluable resource for studies in cell biology and cancer research.Cblc is known to play a key role in regulating intracellular signaling pathways that control cell growth and differentiation. Dysregulation of Cblc expression or function has been implicated in various diseases, including cancer and metabolic disorders.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:CBLC Antibody
SKU:CAB7789
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:DEVQ ERLQ ACRD KPGS YIFR PSCT RLGQ WAIG YVSS DGSI LQTI PANK PLSQ VLLE GQKD GFYL YPDG KTHN PDLT ELGQ AEPQ QRIH VSEE QLQL YWAM DSTF ELCK ICAE SNKD VKIE PCGH LLCS CCLA AWQH SDSQ TCPF CRCE IKGW EAVS IYQF HGQA TAED SGNS SDQE GREL ELGQ VPLS APPL PPRP DLPP RKPR NAQP KVRL LKGN SPPA ALGP QDPA PA
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:CBL-3, RNF57, CBL-SL, CBLC
Positive Sample:293T, Raji, U-937, Mouse kidney
Cellular Localization:Plasma Membrane.
Calculated MW:52kDa
Observed MW:52kDa

This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Purification MethodAffinity purification
Gene ID23624
RRIDAB_2768732
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using CBLC Rabbit pAb (CAB7789) at 1:1000 dilution._Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Basic Kit (AbGn00020)._Exposure time: 90s.
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