ChIP Antibodies

BTNL2 Rabbit Polyclonal Antibody (CAB7120)

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SKU:
CAB7120
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
SS2, BTN7, BTL-II, HSBLMHC1, BTNL2
Research Use:
Cell Biology
Frequently bought together:

Description

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BTNL2 Antibody (CAB7120)

The BTNL2 Antibody (CAB7120) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in various applications, including Western blot analysis. By targeting the BTNL2 protein, this antibody enables the detection and analysis of BTNL2 in different cell types, making it an essential tool for studies in immunology and cancer research.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:BTNL2 Antibody
SKU:CAB7120
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:LKVN GPSQ PILV RVGE DIQL TCYL SPKA NAQS MEVR WDRS HRYP AVHV YMDG DHVA GEQM AEYR GRTV LVSD AIDE GRLT LQIL SARP SDDG QYRC LFEK DDVY QEAS LDLK VVSL GSSP LITV EGQE DGEM QPMC SSDG WFPQ PHVP WRDM EGKT IPSS SQAL TQGS HGLF HVQT LLRV TNIS AVDV TCSI SIPF LGEE KIAT FSLS GW
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:1000 - 1:5000
IHC-P1:100 - 1:500
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:SS2, BTN7, BTL-II, HSBLMHC1, BTNL2
Positive Sample:293T transfected with BTNL2
Cellular Localization:Membrane, Single-Pass Type Ii Membrane Protein.
Calculated MW:50kDa
Observed MW:65kDa

This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer.

Purification MethodAffinity purification
Gene ID56244
RRIDAB_2767675
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and 293T cells transfected with BTNL2 using BTNL2 Rabbit pAb (CAB7120) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 60s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Rat kidney using BTNL2 Rabbit pAb (CAB7120) at dilution of 1:400 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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