Cell Biology Antibodies 12

ARHGEF3 Rabbit Polyclonal Antibody (CAB8490)

(No reviews yet) Write a Review
SKU:
CAB8490
Product Type:
Antibody
Applications:
WB
Applications:
IHC
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse
Synonyms:
GEF3, STA3, XPLN, ARHGEF3
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

ARHGEF3 Antibody (CAB8490)

The ARHGEF3 Antibody (CAB8490) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ARHGEF3 protein, researchers can easily detect and analyze this important molecule in various cell types, making it an invaluable asset for studies in oncology and metastasis research.ARHGEF3, also known as Rho guanine nucleotide exchange factor 3, plays a crucial role in promoting cancer cell migration and invasion by activating Rho GTPases.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:ARHGEF3 Antibody
SKU:CAB8490
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:LEEA INII QGIV AEIN TKTG ESEC RYYK ERLL YLEE GQKD SLID SSRV LCCH GELK NNRG VKLH VFLF QEVL VITR AVTH NEQL CYQL YRQP IPVK DLLL EDLQ DGEV RLGG SLRG AFSN NERI KNFF RVSF KNGS QSQT HSLQ ANDT FNKQ QWLN CIRQ AKET VLCA AGQA GVLD SEGS FLNP TTGS RELQ GETK LEQM DQSD SESD CSMD TSEV SLDC ERME QTDS SCGN SRHG ESNV
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:GEF3, STA3, XPLN, ARHGEF3
Positive Sample:MCF7, HepG2
Cellular Localization:Cytoplasm.
Calculated MW:60kDa
Observed MW:60kDa

Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID50650
RRIDAB_2768434
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using ARHGEF3 Rabbit pAb (CAB8490) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 60s.
View AllClose

0 Reviews

View AllClose

Related Products