Cell Biology Antibodies 8

ARHGDIB Rabbit Polyclonal Antibody (CAB3740)

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SKU:
CAB3740
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
Antibody Type:
Polyclonal Antibody
Reactivity:
Human, Mouse
Synonyms:
D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2, ARHGDIB
Research Use:
Cell Biology
Frequently bought together:

Description

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ARHGDIB Antibody (CAB3740)

The ARHGDIB Antibody (CAB3740) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced through rabbit immunization, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the ARHGDIB protein, this antibody enables researchers to detect and analyze ARHGDIB expression in various cell types.ARHGDIB, also known as RhoGDI beta, plays a key role in regulating the activity of Rho GTPases, which are important for intracellular signaling and cell movement.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:ARHGDIB Antibody
SKU:CAB3740
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MTEK APEP HVEE DDDD ELDS KLNY KPPP QKSL KELQ EMDK DDES LIKY KKTL LGDG PVVT DPKA PNVV VTRL TLVC ESAP GPIT MDLT GDLE ALKK ETIV LKEG SEYR VKIH FKVN RDIV SGLK YVQH TYRT GVKV DKAT FMVG SYGP RPEE YEFL TPVE EAPK GMLA RGTY HNKS FFTD DDKQ DHLS WEWN LSIK KEWT E
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2, ARHGDIB
Positive Sample:Raji, HL-60, HT-1080, Mouse brain, Mouse lung
Cellular Localization:Cytoplasm.
Calculated MW:23kDa
Observed MW:23kDa

Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).

Purification MethodAffinity purification
Gene ID397
RRIDAB_2765242
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using ARHGDIB Rabbit pAb (CAB3740) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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