SIRT6 Polyclonal Antibody
- SKU:
- CAB21535
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | SIRT6 Polyclonal Antibody |
| Product Code: | CAB21535 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Nucleus, nucleoplasm |
This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 251-355 of human SIRT6 (NP_057623.2). |
| Sequence: | DLRIH GYVDE VMTRL MKHLG LEIPA WDGPR VLERA LPPLP RPPTP KLEPK EESPT RINGS IPAGP KQEPC AQHNG SEPAS PKRER PTSPA PHRPP KRVKA KAVPS |
| Synonyms: | SIR2L6, hSIRT6 |
| Calculated MW: | 39kDa |
| Observed MW: | Refer to figures |
Related Products
Doublecortin Polyclonal Antibody
OverviewProduct Name:Doublecortin Polyclonal AntibodyProduct Code:CAB0149Reactivity:Human, MouseApplications:Western blotting, Im