ROR1 Monoclonal Antibody
- SKU:
- CAB24888
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG1
- Applications:
- FC
Description
| Product Name: | ROR1 Monoclonal Antibody |
| Product Code: | CAB24888 |
| Reactivity: | Human |
| Applications: | Flow Cytometry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG1 |
| Clone No: | ARC63587 |
| Reactivity: | Human |
| Tested Applications: | FC |
| Key Applications: | Flow Cytometry |
| Recommended Dilution: | FC 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-403 of Human ROR1 (NP_005003.2). |
| Sequence: | ARGAA AQETE LSVSA ELVPT SSWNI SSELN KDSYL TLDEP MNNIT TSLGQ TAELH CKVSG NPPPT IRWFK NDAPV VQEPR RLSFR STIYG SRLRI RNLDT TDTGY FQCVA TNGKE VVSST GVLFV KFGPP PTASP GYSDE YEEDG FCQPY RGIAC ARFIG NRTVY MESLH MQGEI ENQIT AAFTM IGTSS HLSDK CSQFA IPSLC HYAFP YCDET SSVPK PRDLC RDECE ILENV LCQTE YIFAR SNPMI LMRLK LPNCE DLPQP ESPEA ANCIR IGIPM ADPIN KNHKC YNSTG VDYRG TVSVT KSGRQ CQPWN SQYPH THTFT ALRFP ELNGG HSYCR NPGNQ KEAPW CFTLD ENFKS DLCDI PACDS KDSKE KNKME |
| Synonyms: | NTRKR1, dJ537F10.1 |
| Calculated MW: | 104kDa |
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