RhoC Polyclonal Antibody
- SKU:
- CAB21798
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | RhoC Polyclonal Antibody |
| Product Code: | CAB21798 |
| Reactivity: | Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Rat heart |
| Cellular Location: | Cell membrane, Cleavage furrow, Cytoplasmic side, Lipid-anchor |
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 94-193 of human RhoC (NP_786886.1). |
| Sequence: | NIPEK WTPEV KHFCP NVPII LVGNK KDLRQ DEHTR RELAK MKQEP VRSEE GRDMA NRISA FGYLE CSAKT KEGVR EVFEM ATRAG LQVRK NKRRR GCPIL |
| Synonyms: | H9, ARH9, ARHC, RHOH9 |
| Calculated MW: | 22kDa |
| Observed MW: | 22kDa |
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