Rhesus macaque CD27/TNFRSF7 Recombinant Protein (RPES3855)
- SKU:
- RPES3855
- Product Type:
- Recombinant Protein
- Species:
- Monkey
Description
Rhesus macaque CD27/TNFRSF7 Recombinant Protein
CD27 antigen, also known as CD27L receptor, T-cell activation antigen CD27, T14, S152, Tp55, TNFRSF7 and Tumor necrosis factor receptor for superfamily member 7?belongs to the TNF-receptor superfamily. CD27 is a single-pass type I membrane protein and exists as a homodimer form, containing three TNFR-Cys repeats. CD27 transduces signals that lead to the activation of NF-KappaB and MAPK8/JNK. CD27 is involved in regulating B-cell activation and immunoglobulin synthesis, binding to the ligand CD70. TRAF2 and TRAF5 have been shown to mediate the signaling process of CD27. CD27-binding protein (SIVA), which is a proapoptotic protein, can bind to CD27 and is thought to play a key role in the apoptosis. CD27 is required for generation and long-term maintenance of T cell immunity.
| Product Name: | Rhesus macaque CD27/TNFRSF7 Recombinant Protein (RPES3855) |
| Product Code: | RPES3855 |
| Size: | 10µg |
| Species: | Rhesus macaque |
| Expressed Host: | Human Cells |
| Synonyms: | CD27 Antigen, CD27L Receptor, T-Cell Activation Antigen CD27, T14, Tumor Necrosis Factor Receptor Superfamily Member 7, CD27, CD27, TNFRSF7 |
| Accession: | F7BYS2 |
| Sequence: | Thr21-Ile192 |
| Fusion tag: | C-Fc |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Rhesus macaque CD27 is produced by our Mammalian expression system and the target gene encoding Thr21-Ile192 is expressed with a Fc tag at the C-terminus. |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
| Mol Mass: | 46.5 kDa |
| AP Mol Mass: | 60-90 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mMTris,150mM NaCl,pH8.5. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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