Mouse CD27/TNFRSF7 Recombinant Protein (RPES4700)
- SKU:
- RPES4700
- Product Type:
- Recombinant Protein
- Species:
- Mouse
Frequently bought together:
Description
system_update_altDatasheet
Mouse CD27/TNFRSF7 Recombinant Protein
Mouse CD27 is a single-pass type I membrane protein which is a member of the tumor necrosis factor receptor superfamily. CD27 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. CD27 transduces signals that lead to the activation of NF-?B and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
| Product Name: | Mouse CD27/TNFRSF7 Recombinant Protein (RPES4700) |
| Product Code: | RPES4700 |
| Size: | 10µg |
| Species: | Mouse |
| Expressed Host: | Human Cells |
| Synonyms: | CD27 antigen, CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7,S152,Tnfrsf7,Tp55 |
| Accession: | NP_001028298.1 |
| Sequence: | Pro24-Arg182 |
| Fusion tag: | C-Fc-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Mouse CD27 antigen is produced by our Mammalian expression system and the target gene encoding Pro24-Arg182 is expressed with a Fc, 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by SDS-PAGE |
| Mol Mass: | 45.8 kDa |
| AP Mol Mass: | 60-66 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |