PRDX1/PRDX2 Polyclonal Antibody
- SKU:
- CAB23438
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IF
Description
| Product Name: | PRDX1/PRDX2 Polyclonal Antibody |
| Product Code: | CAB23438 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | IF/ICC, ELISA |
| Key Applications: | Immunofluorescence |
| Recommended Dilution: | IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm |
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human PRDX1/PRDX2 (NP_859428.1). |
| Sequence: | MASGN ARIGK PAPDF KATAV VDGAF KEVKL SDYKG KYVVL FFYPL DFTFV CPTEI IAFSN RAEDF RKLGC EVLGV SVDSQ FTHLA WYEQG PKREV AAKLT PSGPS SVASW PLLNL WNLRF PIVKI METLP PKSLR MMTVI SI |
| Synonyms: | PRP, TSA, PRX2, PTX1, TPX1, NKEFB, PRXII, TDPX1, NKEF-B, HEL-S-2a |
| Calculated MW: | 22kDa |
| Observed MW: | Refer to figures |
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