The Peroxiredoxin 1/PAG Monoclonal Antibody (CAB4956) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity for PRDX1 in human samples, making it ideal for various applications such as Western blotting.PRDX1, also known as peroxiredoxin 1, plays a crucial role in protecting cells from oxidative stress and maintaining cellular homeostasis. Its dysregulation has been linked to various diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
Peroxiredoxin 1/PAG Monoclonal Antibody
SKU:
CAB4956
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Clone Number:
ARC1274
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene.
Purification Method
Affinity purification
Gene ID
5052
RRID
AB_2863397
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Peroxiredoxin 1/PAG Rabbit mAb (CAB4956) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
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