Cell Biology Antibodies 4

Peroxiredoxin 1/PAG Rabbit Polyclonal Antibody (CAB13524)

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SKU:
CAB13524
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse
Synonyms:
PAG, PAGA, PAGB, PRX1, PRXI, MSP23, NKEFA, TDPX2, NKEF-A, Peroxiredoxin 1/PAG
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

Peroxiredoxin 1/PAG Antibody (CAB13524)

The Peroxiredoxin 1/PAG Antibody (CAB13524) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, exhibits high specificity towards human samples and has been validated for use in Western blot assays. By binding to the PRDX1 protein, it enables precise detection and analysis in various cell types, making it well-suited for investigations in oxidative stress, cancer biology, and neurodegenerative diseases.PRDX1, also known as peroxiredoxin-1, plays a pivotal role in defending cells against oxidative damage and maintaining cellular health by scavenging harmful reactive oxygen species. Dysregulation of PRDX1 has been linked to various pathologies, including cancer progression, neurodegenerative disorders, and cardiovascular diseases.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:Peroxiredoxin 1/PAG Antibody
SKU:CAB13524
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MSSG NAKI GHPA PNFK ATAV MPDG QFKD ISLS DYKG KYVV FFFY PLDF TFVC PTEI IAFS DRAE EFKK LNCQ VIGA SVDS HFCH LAWV NTPK KQGG LGPM NIPL VSDP KRTI AQDY GVLK ADEG ISFR GLFI IDDK GILR QITV NDLP VGRS VDET LRLV QAFQ FTDK HGEV CPAG WKPG SDTI KPDV QKSK EYFS KQK
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PAG, PAGA, PAGB, PRX1, PRXI, MSP23, NKEFA, TDPX2, NKEF-A, Peroxiredoxin 1/PAG
Positive Sample:HepG2, HeLa, A-549, Mouse liver, Mouse heart
Cellular Localization:Cytoplasm, Melanosome.
Calculated MW:22kDa
Observed MW:24kDa

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene.

Purification MethodAffinity purification
Gene ID5052
RRIDAB_2760385
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using Peroxiredoxin 1/PAG Rabbit pAb (CAB13524) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST.
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