Description
| Product Name: | N-Cadherin Polyclonal Antibody |
| Product Code: | CAB21308 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IP, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IP 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, 293T |
| Cellular Location: | Cell membrane, Single-pass type I membrane protein |
This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 807-906 of human N-Cadherin (NP_001783.2). |
| Sequence: | RRMDE RPIHA EPQYP VRSAA PHPGD IGDFI NEGLK AADND PTAPP YDSLL VFDYE GSGST AGSLS SLNSS SSGGE QDYDY LNDWG PRFKK LADMY GGGDD |
| Synonyms: | CDHN, NCAD, ACOGS, ADHD8, CD325, ARVD14, CDw325 |
| Calculated MW: | 100kDa |
| Observed MW: | 140kDa |