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PE/Cyanine7 Anti-Mouse CD49b Antibody [DX5] (AGEL1450)

Datasheet MSDS
SKU AGEL1450
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Applications FC

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Description

system_update_altDatasheetsystem_update_altMSDS

PE/Cyanine7 Anti-Mouse CD49b Antibody [DX5]

The Mouse CD49b Monoclonal Antibody (PE/Cyanine7 Conjugated, DX5-AGEL1450) from Assay Genie is a powerful tool for researchers studying immune cell surface molecules in mice. This antibody is specifically designed to target CD49b, a key integrin involved in cell adhesion and migration processes within the immune system. Developed for use in flow cytometry applications, this antibody is conjugated with PE/Cyanine7, providing researchers with an efficient and reliable method for identifying and characterizing CD49b-expressing cells in mouse samples. CD49b, also known as DX5, is a well-known marker for natural killer (NK) cells and some subsets of T cells in mice.

By targeting CD49b, researchers can better understand the roles of these immune cell populations in various physiological and pathological processes, including immune responses to infections, tumor surveillance, and autoimmune diseases.The Mouse CD49b Monoclonal Antibody (PE/Cyanine7 Conjugated, DX5-AGEL1450) from Assay Genie is a valuable tool for immunologists, cancer researchers, and anyone studying immune cell function in mouse models. With its high specificity and sensitivity, this antibody enables precise detection and analysis of CD49b-expressing cells, making it an essential component of any immunology research toolkit.

Product Title:PE/Cyanine7 Anti-Mouse CD49b Antibody [DX5]
SKU:AGEL1450
Size:25µg, 100µg
Clone No:DX5
Synonyms:Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62469
Gene ID:16398
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.
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