Description
Product Name: | METTL3 Polyclonal Antibody |
Product Code: | CAB21572 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IP, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:10-1:20, IHC-P 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | NIH/3T3, Mouse testis, Rat thymus |
Cellular Location: | Nucleus speckle |
This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-156 of human METTL3 (NP_062826.2). |
Sequence: | MSDTW SSIQA HKKQL DSLRE RLQRR RKQDS GHLDL RNPEA ALSPT FRSDS PVPTA PTSGG PKPST ASAVP ELATD PELEK KLLHH LSDLA LTLPT DAVSI CLAIS TPDAP ATQDG VESLL QKFAA QELIE VKRGL LQDDA HPTLV TYADH SKLSA M |
Synonyms: | M6A, IME4, Spo8, MT-A70, hMETTL3 |
Calculated MW: | 64kDa |
Observed MW: | 70kDa |