Human UQCRC1 Recombinant Protein (RPPB5088)

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SKU:
RPPB5088
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P31930

Description

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Product Name:Human UQCRC1 Recombinant Protein
Product Code:RPPB5088
Size:20µg
Species:Human
Target:UQCRC1
Synonyms:D3S3191, QCR1, UQCR1, Cytochrome b-c1 complex subunit 1, mitochondrial, ComplexIII subunit 1, Core protein I, Ubiquinol-cytochrome-c reductase complex coreprotein 1.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:UQCRC1 protein solution (1mg/ml) contains 20mM Tris-HCl buffer(pH 8.0), 0.4M UREA and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 85.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSEFTATFA QALQFVPETQ VSLLDNGLRV ASEQSSQPTC TVGVWIDVGS RFETEKNNGA GYFLEHLAFK GTKNRPGSAL EKEVESMGAH LNAYSTREHT AYYIKALSKD LPKAVELLGD IVQNCSLEDS QIEKERDVIL REMQENDASM RDVVFNYLHA TAFQGTPLAQ AVEGPSENVR KLSRADLTEY LSTHYKAPRM VLAAAGGVEH QQLLDLAQKH LGGIPWTYAE DAVPTLTPCR FTGSEIRHRD DALPFAHVAI AVEGPGWASP DNVALQVANA IIGHYDCTYG GGVHLSSPLA SGAVANKLCQ SFQTFSICYA ETGLLGAHFV CDRMKIDDMM FVLQGQWMRL CTSATESEVA RGKNILRNAL VSHLDGTTPV CEDIGRSLLT YGRRIPLAEW ESRIAEVDAS VVREICSKYI YDQCPAVAGY GPIEQLPDYN RIRSGMFWLR F

Ubiquinol-Cytochrome CReductase Core Protein I (UQCRC1) is a member of the peptidase M16 family,UQCRC1/QCR1 subfamily. UQCRC1 is a part of the ubiquinol-cytochrome creductase complex (complex III or cytochrome b-c1 complex), which is component ofthe mitochondrial respiratory chain. UQCRC1 can mediate formation of thecomplex between cytochromes c and c1.

UQCRC1 Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 471 amino acids (35-480 a.a) andhaving a molecular mass of 51.8kDa.UQCRC1 is fused to a 25 amino acid His-tag at N-terminus &purified by proprietary chromatographic techniques.

UniProt Protein Function:UQCRC1: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily.
UniProt Protein Details:

Protein type:Mitochondrial; Energy Metabolism - oxidative phosphorylation; EC 1.10.2.2; Oxidoreductase

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex III; mitochondrial respiratory chain

Molecular Function:metal ion binding; ubiquinol-cytochrome-c reductase activity; protein complex binding

Biological Process: response to alkaloid; cellular metabolic process; aerobic respiration; response to activity; oxidative phosphorylation; mitochondrial electron transport, ubiquinol to cytochrome c

UniProt Code:P31930
NCBI GenInfo Identifier:92090651
NCBI Gene ID:7384
NCBI Accession:P31930.3
UniProt Secondary Accession:P31930,Q96DD2, B2R7R8,
UniProt Related Accession:P31930
Molecular Weight:52,646 Da
NCBI Full Name:Cytochrome b-c1 complex subunit 1, mitochondrial
NCBI Synonym Full Names:ubiquinol-cytochrome c reductase core protein I
NCBI Official Symbol:UQCRC1��
NCBI Official Synonym Symbols:QCR1; UQCR1; D3S3191��
NCBI Protein Information:cytochrome b-c1 complex subunit 1, mitochondrial; core protein I; complex III subunit 1; ubiquinol-cytochrome-c reductase complex core protein 1
UniProt Protein Name:Cytochrome b-c1 complex subunit 1, mitochondrial
UniProt Synonym Protein Names:Complex III subunit 1; Core protein I; Ubiquinol-cytochrome-c reductase complex core protein 1
UniProt Gene Name:UQCRC1��
UniProt Entry Name:QCR1_HUMAN
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