Human JMJD7 Recombinant Protein (RPPB3770)

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RPPB3770

Description

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Product Name:Human JMJD7 Recombinant Protein
Product Code:RPPB3770
Size:20µg
Species:Human
Target:JMJD7
Synonyms:Jumonji Domain Containing 7, Jumonji Domain-ContainingProtein 7, JmjC Domain-Containing Protein 7.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:JMJD7 protein solution (1mg/ml) containing 20mM Tris-HClbuffer (pH8.0), 10% glycerol and 0.1M NaCl.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Purity:Greaterthan 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMAEAALE AVRSELREFP AAARELCVPL AVPYLDKPPT PLHFYRDWVCPNRPCIIRNA LQHWPALQKW SLPYFRATVG STEVSVAVTP DGYADAVRGD RFMMPAERRL PLSFVLDVLEGRAQHPGVLY VQKQCSNLPS ELPQLLPDLE SHVPWASEAL GKMPDAVNFW LGEAAAVTSL HKDHYENLYC VVSGEKHFLF HPPSDRPFIPYELYTPATYQ LTEEGTFKVV DEEAMEKVPW IPLDPLAPDL ARYPSYSQAQ ALRCTVRAGE MLYLPALWFHHVQQSQGCIA VNFWYDMEYD LKYSYFQLLD SLTKASGLD

JmjC domain-containing protein 7 (JMJD7) is a member of theJMJD family. JMJD7 encodes highly conserved proteins with a JmjC domain, whichare part of the cupin metalloenzyme superfamily. JMJD7 was first thought to bean alternatively spliced isoform of PLA2G4B. It is derived from JMJD7 which islocated upstream of PLA2G4B. Most tissues also express read-through transcriptsfrom JMJD7 into the downstream PLA2G4B gene, some of which may encode fusionproteins combining the N-terminus of JMJD7 with PLA2G4B protein.

JMJD7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 339 amino acids (1-316 a.a) and having a molecular mass of 38.3kDa.JMJD7 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:JMJD7: a highly conserved protein with a JmjC domain, which are part of the cupin metalloenzyme superfamily. JmjC proteins may function as 2-oxoglutarate-Fe(II)-dependent dioxygenases. Most tissues also express read-through transcripts from this gene into the downstream phospholipase A2, group IVB (cytosolic) gene, some of which may encode fusion proteins combining the N-terminus of this protein with the phospholipase A2, group IVB protein. [RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:Unknown function

Chromosomal Location of Human Ortholog: 15q15.1

NCBI Summary:This gene encodes a highly conserved protein with a JmjC domain, which are part of the cupin metalloenzyme superfamily. JmjC proteins may function as 2-oxoglutarate-Fe(II)-dependent dioxygenases. Most tissues also express read-through transcripts from this gene into the downstream phospholipase A2, group IVB (cytosolic) gene, some of which may encode fusion proteins combining the N-terminus of this protein with the phospholipase A2, group IVB protein. [provided by RefSeq, Jul 2008]
UniProt Code:P0C870
NCBI GenInfo Identifier:205783894
NCBI Gene ID:100137047
NCBI Accession:P0C870.1
UniProt Secondary Accession:P0C870,O95712, Q59GF9, Q8TB10, Q9UKV7, A5D6V5,
UniProt Related Accession:P0C870
Molecular Weight:35,932 Da
NCBI Full Name:JmjC domain-containing protein 7
NCBI Synonym Full Names:jumonji domain containing 7
NCBI Official Symbol:JMJD7��
NCBI Protein Information:jmjC domain-containing protein 7; jumonji domain-containing protein 7
UniProt Protein Name:JmjC domain-containing protein 7
UniProt Synonym Protein Names:Jumonji domain-containing protein 7
Protein Family:JmjC domain-containing protein
UniProt Gene Name:JMJD7��
UniProt Entry Name:JMJD7_HUMAN
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Additional Information

Product Type:
Recombinant Protein
Species:
Human
Uniprot:
P0C870
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