Name: Human GABRβ3 (GABRB3) Recombinant Protein (His tag)
SKU: RPES5572
Availability: OutOfStock

Human GABRβ3 (GABRB3) Recombinant Protein (His tag)

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SKU:

RPES5572

Description

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Additional Information

Product Type:	Recombinant Protein
Species:	Human

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Mol Mass:	24.09 kDa
AP Mol Mass:	32 kDa
Tag:	N-His & C-His
Purity:	> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:	Please contact us for more information.
Bio Activity:	Testing in progress

Sequence:	Ser 26-Tyr 245
Accession:	P28472
Storage:	Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:	This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:	Please refer to the printed manual for detailed information.
Background:	γ-aminobutyric acid type A receptor β3 subunit (GABRB3) is a candidate gene for autism spectrum conditions (ASC). Alteration in the gene results in increased tactile sensitivity, or hypersensitivity.Overexpression of GABRB3 might be implicated in the pathogenesis of heroin dependence. Aberration or mutation of this gene leads to neurodevelopmental disorders, such as Angelman syndrome, Prader-Willi syndrome and schizophrenia.[1][3] GABRB3 polymorphisms results in nonsyndromic cleft lip and/or palate (NSCL/P).