Description
Product Name: | HNRNPA2B1 Polyclonal Antibody |
Product Code: | CAB21802 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Recommended Dilution: | WB 1:100-1:500, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Cellular Location: | Cytoplasm, Nucleus, nucleoplasm |
This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human HNRNPA2B1 (NP_112533.1). |
Sequence: | MEKTL ETVPL ERKKR EKEQF RKLFI GGLSF ETTEE SLRNY YEQWG KLTDC VVMRD PASKR SRGFG FVTFS SMAEV DAAMA ARPHS IDGRV VEPKR AVARE ESGKP GAHVT VKKLF VGGIK EDTEE HHLRD YFEEY GKIDT IEIIT DRQSG KKRGF GFVTF DDHDP VDKIV LQKYH TINGH |
Synonyms: | RNPA2, HNRPA2, HNRPB1, SNRPB1, HNRNPA2, HNRNPB1, IBMPFD2, HNRPA2B1 |
Calculated MW: | 37kDa |
Observed MW: | Refer to figures |