GNA11 Polyclonal Antibody (CAB19313)

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SKU:
CAB19313
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
Applications:
IF
Reactivity:
Human, Mouse, Rat
Synonyms:
FBH, FBH2, FHH2, HG1K, HHC2, GNA-11, HYPOC2, GNA11
Frequently bought together:

Description

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GNA11 Polyclonal Antibody (CAB19313)

The GNA11 Polyclonal Antibody (CAB19313) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, generated in rabbits, is highly specific to human samples and is validated for use in immunohistochemistry and ELISA applications. By binding to the GNA11 protein, this antibody allows for the detection and analysis of GNA11 expression in a variety of cell types, making it an ideal choice for studies in oncology and signal transduction research.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:GNA11 Polyclonal Antibody
SKU:CAB19313
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:ESKA LFRT IITY PWFQ NSSV ILFL NKKD LLED KILY SHLV DYFP EFDG PQRD AQAA REFI LKMF VDLN PDSD KIIY SHFT CATD TENI RFVF AAVK DTIL Q
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:2000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:FBH, FBH2, FHH2, HG1K, HHC2, GNA-11, HYPOC2, GNA11
Positive Sample:BxPC-3, PC-3
Cellular Localization:Cell Membrane, Cytoplasm, Lipid-Anchor.
Calculated MW:42kDa
Observed MW:42kDa

The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.

Purification MethodAffinity purification
Gene ID2767
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using GNA11 Rabbit pAb (CAB19313) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates / proteins: 25 μg per lane. Blocking buffer: 3 % nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
Product ImageImmunofluorescence analysis of NIH/3T3 cells using GNA11 Rabbit pAb (CAB19313) at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
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