GALT Polyclonal Antibody
- SKU:
- CAB21426
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | GALT Polyclonal Antibody |
| Product Code: | CAB21426 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | cytoplasm, cytosol, Golgi apparatus |
Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-379 of human GALT (NP_000146.2). |
| Sequence: | MSRSG TDPQQ RQQAS EADAA AATFR ANDHQ HIRYN PLQDE WVLVS AHRMK RPWQG QVEPQ LLKTV PRHDP LNPLC PGAIR ANGEV NPQYD STFLF DNDFP ALQPD APSPG PSDHP LFQAK SARGV CKVMC FHPWS DVTLP LMSVP EIRAV VDAWA SVTEE LGAQY PWVQI FENKG AMMGC SNPHP HCQVW ASSFL PDIAQ REERS QQAYK SQHGE PLLME YSRQE LLRKE RLVLT SEHWL VLVPF WATWP YQTLL LPRRH VRRLP ELTPA ERDDL ASIMK KLLTK YDNLF ETSFP YSMGW HGAPT GSEAG ANWNH WQLHA HYYPP LLRSA TVRKF MVGYE MLAQA QRDLT PEQAA ERLRA LPEVH YHLGQ KDRET ATIA |
| Synonyms: | GALT, galactose-1-phosphate uridylyltransferase |
| Calculated MW: | 43kDa |
| Observed MW: | Refer to figures |
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