Description
Product Name: | Engrailed 1 Polyclonal Antibody |
Product Code: | CAB23060 |
Reactivity: | Human, Mouse, Rat |
Applications: | Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | IF/ICC, ELISA |
Key Applications: | Immunofluorescence |
Recommended Dilution: | IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Cellular Location: | nucleus |
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.
Immunogen: | Recombinant protein of human Engrailed 1. |
Sequence: | KLKKK KNEKE DKRPR TAFTA EQLQR LKAEF QANRY ITEQR RQTLA QELSL NESQI KIWFQ NKRAK IKKAT GIKNG LALHL MAQGL YNHST TTVQD KDESE |
Synonyms: | ENDOVESLB |
Calculated MW: | 40kDa |
Observed MW: | Refer to figures |