DNAJC2 Polyclonal Antibody
- SKU:
- CAB21431
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | DNAJC2 Polyclonal Antibody |
| Product Code: | CAB21431 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Cytoplasm, Nucleus, cytosol |
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human DNAJC2 (NP_055192.1). |
| Sequence: | MLLLP SAADG RGTAI THALT SASTL CQVEP VGRWF EAFVK RRNRN ASASF QELED KKELS EESED EELQL EEFPM LKTLD PKDWK NQDHY AVLGL GHVRY KATQR QIKAA HKAMV LKHHP DKRKA AGEPI KEGDN DYFTC |
| Synonyms: | ZRF1, ZUO1, MPP11, MPHOSPH11 |
| Calculated MW: | 72kDa |
| Observed MW: | Refer to figures |
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