Epigenetics & Nuclear Signaling Antibodies 3

DNAJC2 Rabbit Polyclonal Antibody (CAB4633)

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SKU:
CAB4633
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
Reactivity:
Human, Mouse
Synonyms:
ZRF1, ZUO1, MPP11, MPHOSPH11, DNAJC2
Research Use:
Epigenetics and Nuclear Signaling
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Description

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DNAJC2 Antibody (CAB4633)

The DNAJC2 Antibody (CAB4633) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding to the DNAJC2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for studies in molecular biology and protein folding mechanisms.DNAJC2, also known as DnaJ homolog subfamily C member 2, plays a crucial role in ensuring proper protein folding and preventing protein aggregation within cells.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:DNAJC2 Antibody
SKU:CAB4633
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MLLL PSAA DGRG TAIT HALT SAST LCQV EPVG RWFE AFVK RRNR NASA SFQE LEDK KELS EESE DEEL QLEE FPML KTLD PKDW KNQD HYAV LGLG HVRY KATQ RQIK AAHK AMVL KHHP DKRK AAGE PIKE GDND YFTC
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:ZRF1, ZUO1, MPP11, MPHOSPH11, DNAJC2
Positive Sample:HeLa, Mouse thymus
Cellular Localization:Cytoplasm, Nucleus, Cytosol.
Calculated MW:72kDa
Observed MW:80kDa

This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described.

Purification MethodAffinity purification
Gene ID27000
RRIDAB_2765796
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using DNAJC2 Rabbit pAb (CAB4633) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageWestern blot analysis of various lysates using DNAJC2 Rabbit pAb (CAB4633) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates / proteins: 25 μg per lane. Blocking buffer: 3 % nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
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