Chrm1 Antibody (PACO25749)
- SKU:
- PACO25749
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Chrm1 Antibody (PACO25749) |
| Antibody SKU: | PACO25749 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Muscarinic acetylcholine receptor M1 protein (210-366AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot Positive WB detected in: Rat brain tissue All lanes: Chrm1 antibody at 5.5µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 52 kDa Observed band size: 52 kDa . |
| Background: | The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. |
| Synonyms: | Muscarinic acetylcholine receptor M1, Chrm1, Chrm-1 |
| UniProt Protein Function: | mAChR m1: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM1 sub-subfamily.Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integralCellular Component: asymmetric synapse; cell junction; dendrite; integral to plasma membrane; nerve terminal; plasma membrane; postsynaptic density; postsynaptic membrane; synapseMolecular Function: drug binding; G-protein coupled acetylcholine receptor activityBiological Process: acetylcholine receptor signaling, muscarinic pathway; cognition; muscarinic acetylcholine receptor, adenylate cyclase inhibiting pathway; muscarinic acetylcholine receptor, phospholipase C activating pathway; neuromuscular synaptic transmission; positive regulation of ion transport; regulation of locomotion; regulation of vascular smooth muscle contraction; saliva secretion; synaptic transmission, cholinergic |
| UniProt Protein Details: | |
| NCBI Summary: | plays a role in acetylcholine receptor signaling and neuromuscular synaptic transmission [RGD, Feb 2006] |
| UniProt Code: | P08482 |
| NCBI GenInfo Identifier: | 18249941 |
| NCBI Gene ID: | 25229 |
| NCBI Accession: | NP_542951.1 |
| UniProt Secondary Accession: | P08482 |
| UniProt Related Accession: | P08482 |
| Molecular Weight: | 51,369 Da |
| NCBI Full Name: | muscarinic acetylcholine receptor M1 |
| NCBI Synonym Full Names: | cholinergic receptor, muscarinic 1 |
| NCBI Official Symbol: | Chrm1 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | muscarinic acetylcholine receptor M1 |
| UniProt Protein Name: | Muscarinic acetylcholine receptor M1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Microtubule-associated protein |
| UniProt Gene Name: | Chrm1 |
| UniProt Entry Name: | ACM1_RAT |
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