CD61 monoclonal antibody (APC) (AGIM0480)

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SKU:
AGIM0480
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
CLB-thromb/1, C17
Conjugation:
APC
Applications:
FC

Description

system_update_altDatasheet
Product Name:CD61 monoclonal antibody (APC)
Product Code:AGIM0480
Size:100 µL
Reactivity:Human
Clone:CLB-thromb/1, C17
Applications:Flow Cytometry, Immunofluorescence
Conjugate:APC
Isotype:IgG1
Host Species:Mouse
Storage:Store at 4°C. Avoid prolonged exposure to light.
Background:CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells. CD61 is a useful marker of megakaryoblasts and megakaryoblastic leukaemias and inhibits binding of ligand (fibrinogen, fibronectin, etc.).
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