Name: CD61 monoclonal antibody (APC) (AGIM0480)
SKU: AGIM0480
Availability: OutOfStock

CD61 monoclonal antibody (APC) (AGIM0480)

(No reviews yet) Write a Review

SKU:

AGIM0480

Description

View AllClose

Additional Information

View AllClose

OverviewAntibody Name:Human CD61 Monoclonal Antibody (APC Conjugated)Antibody Code:AGEL1827Size:50 TestsClone:VI-PL2Sy

system_update_altDatasheetOverview

OverviewProduct Name:APC Monoclonal AntibodyProduct Code:CAB22073Reactivity:Human, Mouse, RatApplications:Western blotting, Immun

OverviewAntibody Name:Human CD61 Monoclonal Antibody (PE Conjugated)Antibody Code:AGEL1826Size:50 TestsClone:VI-PL2Syn

system_update_altDatasheetOverview

Isotype:	IgG1
Host Species:	Mouse
Storage:	Store at 4°C. Avoid prolonged exposure to light.
Background:	CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells. CD61 is a useful marker of megakaryoblasts and megakaryoblastic leukaemias and inhibits binding of ligand (fibrinogen, fibronectin, etc.).