Description
Product Name: | B7-H4 / B7S1 / B7x Polyclonal Antibody |
Product Code: | CAB24542 |
Reactivity: | Mouse |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Mouse |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:1000-1:5000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | Mouse testis |
Cellular Location: | Cell membrane, Single-pass type I membrane protein |
This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-259 of human B7-H4 / B7S1 / B7x (NP_078902.2). |
Sequence: | LIIGF GISGR HSITV TTVAS AGNIG EDGIL SCTFE PDIKL SDIVI QWLKE GVLGL VHEFK EGKDE LSEQD EMFRG RTAVF ADQVI VGNAS LRLKN VQLTD AGTYK CYIIT SKGKG NANLE YKTGA FSMPE VNVDY NASSE TLRCE APRWF PQPTV VWASQ VDQGA NFSEV SNTSF ELNSE NVTMK VVSVL YNVTI NNTYS CMIEN DIAKA TGDIK VTESE IKRRS HLQLL NSKAS |
Synonyms: | VTCN1, B7-H4, B7H4, B7S1, B7X, B7h.5, PRO1291, VCTN1, V-set domain-containing T-cell activation inhibitor 1 |
Calculated MW: | 9kDa/18kDa/20kDa/30kDa |
Observed MW: | 75kDa |