Description
Product Name: | ATAD3A/ATAD3B Polyclonal Antibody |
Product Code: | CAB22703 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunofluorescence |
Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Positive Samples: | HeLa, A-549, U-251MG |
Cellular Location: | Mitochondrion inner membrane, Peripheral membrane protein |
The protein encoded by this gene is localized to the mitochondrial inner membrane, where it can bind to a highly-related protein, ATAD3A. ATAD3A appears to interact with matrix nucleoid complexes, and the encoded protein negatively regulates that interaction. This gene is expressed almost exclusively in pluripotent embryonic stem cells and some cancer cells. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ATAD3B (NP_114127.3). |
Sequence: | MSWLF GVNKG PKGEG AGPPP PLPPA QPGAE GGGDR GLGDR PAPKD KWSNF DPTGL ERAAK AAREL EHSRY AKEAL NLAQM QEQTL QLEQQ SKLKE YEAAV EQLKS EQIRA QAEER RKTLS EETRQ HQARA QYQDK LARQR YEDQL KQQQL LNEEN LRKQE ESVQK QEAMR RATVE REMEL RHKNE MLRVE TEARA RAKAE RENAD IIREQ IRLKA SEHRQ TVLES IRTAG TLFGE GFRAF |
Synonyms: | TOB3, AAA-TOB3 |
Calculated MW: | 71/73kDa |
Observed MW: | 68kDa |